Ritonavir-Boosted Nirmatrelvir (Paxlovid)
Nirmatrelvir is an orally bioavailable protease inhibitor that is active against MPRO, a viral protease that plays an essential role in...
Remdesivir
Remdesivir is a nucleotide prodrug of an adenosine analog. It binds to the viral RNA-dependent RNA polymerase and inhibits viral...
The ACG Clinical Practice Guideline on UpperGastrointestinal and Ulcer Bleeding Review
Abstract and Introduction Introduction Gastrointestinal bleeding (GIB) is a common cause of hospitalization. Upper gastrointestinal...
Smoke inhalation Injury
Practice Essentials Smoke inhalation is the leading cause of death due to fires. It produces injury through several mechanisms, including...
Hypernatremia in Emergency Medicine
Practice Essentials Sodium levels are tightly controlled in a healthy individual by regulation of urine concentration and an intact...
Initial Evaluation and Management of the Burn Patient
Overview Outcomes for burn patients have improved dramatically over the past 20 years, yet burns still cause substantial morbidity and...
Hypokalemia in Emergency Medicine
Practice Essentials Hypokalemia is defined as a potassium level of less than 3.5 mEq/L, while moderate hypokalemia is a serum level of...
Hyperkalemia in Emergency Medicine
Practice Essentials Hyperkalemia is defined as a potassium level greater than 5.5 mEq/L. [1] It can be difficult to diagnose clinically...
Hypercalcemia in Emergency Medicine
Practice Essentials Hypercalcemia is a disorder that most commonly results from malignancy or primary hyperparathyroidism. [1, 2, 3, 4,...
Calcium Channel Blocker Toxicity
Practice Essentials Ingestion of excessive calcium channel blocker (CCB) agents is one of the most potentially lethal prescription drug...
