

Encephalitis
Practice Essentials Encephalitis presents as diffuse or focal neuropsychological dysfunction. Although it primarily involves the brain,...


Ritonavir-Boosted Nirmatrelvir (Paxlovid)
Nirmatrelvir is an orally bioavailable protease inhibitor that is active against MPRO, a viral protease that plays an essential role in...


Remdesivir
Remdesivir is a nucleotide prodrug of an adenosine analog. It binds to the viral RNA-dependent RNA polymerase and inhibits viral...


Ritonavir-Boosted Nirmatrelvir (Paxlovid)
Nirmatrelvir is an orally bioavailable protease inhibitor that is active against MPRO, a viral protease that plays an essential role in...


Viral Hepatitis
Background Hepatitis, a general term referring to inflammation of the liver, may result from various causes, both infectious (ie, viral,...

Adenovirus Infection
Background Adenovirus, a DNA virus, was first isolated in the 1950s in adenoid tissue–derived cell cultures, hence the name. These...


Trending Clinical Topic: Hepatitis
A worldwide outbreak of acute, severe hepatitis in children has made headlines recently. This is in part because the precise cause has...

HIV Infection and AIDS
Practice Essentials Human immunodeficiency virus (HIV) is a blood-borne virus typically transmitted via sexual intercourse, shared...


Cases of severe acute hepatitis of unknown aetiology in children
Incident Lead Incident Director Health Protection Teams are asked to share this BN with Local Authority Directors of Public Health for...


Public Health Agency statement on acute hepatitis in children
Tuesday, 12 April 2022 The Public Health Agency (PHA) is working with counterparts in other jurisdictions on a UK-wide investigation...