Emergent Management of Pediatric Patients with Fever
Overview Emergent management of pediatric patients with fever is a common challenge. Children with fever account for as many as 20% of...
Cardiac Tamponade
Overview Practice Essentials Cardiac tamponade is a clinical syndrome caused by the accumulation of fluid in the pericardial space,...
Meningococcemia
Practice Essentials Meningococcemia is a bloodstream infection (BSI) caused by Neisseria meningitidis. Its wide variety of acute...
Encephalitis
Practice Essentials Encephalitis presents as diffuse or focal neuropsychological dysfunction. Although it primarily involves the brain,...
Ritonavir-Boosted Nirmatrelvir (Paxlovid)
Nirmatrelvir is an orally bioavailable protease inhibitor that is active against MPRO, a viral protease that plays an essential role in...
Remdesivir
Remdesivir is a nucleotide prodrug of an adenosine analog. It binds to the viral RNA-dependent RNA polymerase and inhibits viral...